Pesquisa sobre: NOGO PROTEINS 
Descritores Encontrados: 1
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Descritor Inglês:   Nogo Proteins 
Descritor Espanhol:   Proteínas Nogo 
Descritor Português:   Proteínas Nogo 
Sinônimos Inglês:   NI-220 Protein
NI-250 Protein
NI-35 Protein
NI-35-250
Neurite Growth Inhibitor 35-350
Nogo Protein
Nogo-66 Protein
Nogo-A Protein
Nogo-B Protein
Nogo-C Protein
Reticulon 4-B Protein
Reticulon-4 Protein
NI 220 Protein
NI 250 Protein
NI 35 250
NI 35 Protein
Neurite Growth Inhibitor 35 350
Nogo 66 Protein
Nogo A Protein
Nogo B Protein
Nogo C Protein
Reticulon 4 B Protein
Reticulon 4 Protein  
Categoria:   D12.776.543.620.738
D12.776.631.580.738
Definição Inglês:   Myelin proteins that are expressed as three isoforms: Nogo-A, Nogo-B, and Nogo-C. These share a C-terminal reticulon homology domain (RHD), consisting of two hydrophobic membrane domains flanking a 66 amino acid (Nogo-66) hydrophilic region. A long transmembrane region allows conformations that either span the entire membrane or fold into a hairpin conformation. Nogo inhibits NEURITE outgrowth and modulates wiring and the restriction of SYNAPTIC PLASTICITY in the adult central nervous system. It also regulates neurite fasciculation, branching, and extension in the developing nervous system. 
Nota Histórica Inglês:   2017 (2000) 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número do Registro:   56639 
Identificador Único:   D000070798 

Ocorrência na BVS:
 

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